Research

This issue's publications

Presentations

Unley High CBNS Roadshow visit

On October 23, the groups of  Clive Prestidge and Benjamin Thierry in conjunction with the ARC Centre of Excellence in Convergent Bio-Nano Science (CBNS) travelled to Unley High School to share insight on nanomedicine with year 9 science students. 52 students received inspiring talks from academic researchers at all stages of their career for a glimpse into what a job in scientific research is really like. The students were given hands-on experience working with nanotechnology and observing how it can be used in everyday life as well as a research laboratory. The Virtual Reality ‘Journey into a cell’ allowed students to take a step inside a single breast cancer cell and observe for themselves how nanoparticles can be used to fight deadly diseases.  See more on the Channel 10 News coverage here  

Ahmed Abdalla has presented his findings on toxicology and polypharmacy with platform presentations at 2 International conferences: The 16th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT) held in Brisbane in September 2018 and The World Congress on Chemistry held in Rome, Italy in November 2018. Ahmed was successful in being awarded several travel awards to support this travel; (The Translational Australian Clinical Toxicology (TACT) program, Sydney University; The Hospital Research Foundation Travel Award from the Basil Hetzel Institute for Translational Medical Research and  from The Adelaide Pharmacology Group. 

PhD student Lemlem Gebremichael has delivered a platform presentation on her work with the eldery and polypharmacy at the Aging and Society: Eighth interdisciplinary Conference in Tokyo, Japan in September 2018. For her travel she was awarded a Translational Australian Clinical Toxicology (TACT) program, Sydney University Travel Award.

PhD student Emma Jaunay (supervisors Susan Semple and Permal Deo) presented at the 13th International Symposium on the Maillard Reaction in Montreal Canada, September 10-13, 2018. Emma's poster was titled 'Fractions of Petalostigma banksii fruits attenuate  Ne-carboxymethyllysine formation'. Permal Deo also attended the conference and gave an oral presentation on 'Effects of advanced glycation endproducts on DNA damage and telomere dynamics'.  

Paul Anderson delivered presentations 'Vitamin D therapy in in bone health' at the Australian and New Zealand Bone and Mineral Society meeting in September in Queenstown, NZ and 'Vitamin D metabolism as bone quality determinants in elderly orthopaedic patient bone' at the American Society for Bone and Mineral Research meeting in October in Montreal.

Mohammad Hassanshahi and Qian Tang presented at The International Conference of Osteoporosis and Bone Research in Suzhou, China in October.  Mohammad received a travel award for his presentation while Qian received an award for the best paper.

Completed postgraduate students

Yi Long 

Protein kinase inhibitors as potential anti-cancer agents: design, synthesis and evaluation

Principal Supervisor: Professor Shudong Wang

Ei Lwin

Evaluation of drug transfer in human breast milk

Principal Supervisor: Professor Sanjay Garg

Research matters update 

My Data Management Plans (myDMP) for HDR students

All commencing PhD and Masters Research students are required to lodge a Data Management Plan. Although it’s not too difficult, you may find that your students find it hard to do. A short video describing how to create a DMP can be found here. The DMP simply describes how data will be stored, secured, and who will own it. Considering data storage and ownership is consistent with the Australian Code for the Responsible Conduct of Research

Competitive grant applications

Grant writing season is upon us, and experienced hands have already been planning and writing for some weeks now. Please remember that if you plan on applying for any of the NHMRC or ARC schemes, you will need to contact the Division Research Office and lodge and Expression of Interest to do so. A short video describing how to lodge an EoI can be found here.  Information on the NHMRC funding schemes for this year can be found here

PMB Symposiums

Bi-Annual School Research Symposium

The School hosted its Bi-Annual School Research Symposium on Monday morning, 24 September and Tuesday afternoon, 25 September 2018 at C3-16 City East Campus.

This event conPMB Symposium 1sisted of many presentations throughout the day from postgraduate students, plus an invited alumni speaker. Approximately 100 attendees attended the event and heard presentations across a range of disciplines that encompass research in the school. Presentations included both 15 minute oral presentations and 5 minute ‘flash talks’. The student presenters did a great job of promoting their research and presentation skills to their peers and mentors, and the presentations were enjoyed by all.

Dr Emily Flies (University of Tasmania), the invited alumni speaker gave an insightful presentation, “Failure, Flies and fun: my science success story”

Prizes were awarded to Valentina Poltavets and Jasmine Karanjia for their presentations and Kristy Gray for the ‘flash talk’.

The Symposiums next year will be held in June and September. The invitation will be sent out early next year, all staff and PhD students are encouraged to attend. 

Publications

Book Chapters

Ciobanu, LG & Baune, BT 2018, 'Gene expression of inflammation markers in depression', in B Baune (ed.), Inflammation and immunity in depression: basic science and clinical applications, Elsevier, Netherlands, ch. 11, online, pp. 199-222.

Abstract

Clifton, P 2018, 'Obesity in the development of cardiovascular disease', in C Hankey (ed), Advanced nutrition and dietetics in obesity, John Wiley and Sons, US, ch. 2.2, pp. 49-55.

No Abstract available

Lai, X, Bazin, J, Webb, S, Crespi, M, Zubieta, C & Conn, SJ 2018, 'CircRNAs in plants', in J Xiao (ed.), Circular RNAs: biogenesis and functions, Springer, Singapore, ch. 26, pp. 329-343.

Abstract

Vitry, AI & Shute, R 2018, 'Access to high-cost medicines in Australia', in ZUD Babar (eds), Equitable access to high-cost pharmaceuticals, Academic Press, UK, ch. 11 , pp. 165-181.

Abstract

 

Journals

Abraham, J, Sinollareddy, M, Roberts, MS, Williams, P, Peake, SL, Lipman, J & Roberts, JA 2018, 'Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically patients with sepsis', International journal of antimicrobial agents, in press, pp. 1-25.

Abstract

Abuhelwa, AY, Mudge, S, Upton, RN & Foster, DJ 2018, 'Mechanistic assessment of the effect of omeprazole on the in vivo pharmacokinetics of itraconazole in healthy volunteers', European journal of drug metabolism and pharmacokinetics, online, pp. 1-15.

Abstract

Adeola, M, Azad, R, Kassie, GM, Shirkey, B, Taffet, G, Liebl, M & Agarwal, K 2018, 'Multicomponent interventions reduce high-risk medications for delirium in hospitalized older adults', Journal of the American Geriatrics Society, vol. 66, no. 8, pp. 1638-1645.

Abstract

Afshin, A, Forouzanfar, MH, Reitsma, MB, Sur, P, Ciobanu, LG & Murray, CJ and 147 other authors 2018, 'Health effects of overweight and obesity in 195 countries over 25 years', New England journal of medicine, vol. 377, no. 1, pp. 13-27.

Abstract

Alahakoon, C, Dassanayake, TL, Gawarammana, IB, Sedgwick, EM, Weerasinghe, VS, Abdalla, A, Roberts, MS & Buckley, NA 2018, 'Prediction of organophosphorus insecticideinduced intermediate syndrome with stimulated concentric needle single fibre electromyography', PLoS one, vol. 13, no. 9, pp. 1-19.

Abstract

Albayaty, YN, Thomas, N, Hasan, S & Prestidge, CA 2018, 'Penetration of topically used antimicrobials through Staphylococcus aureus biofilms: a comparative study using different models', Journal of drug delivery science and technology, vol. 48, pp. 429-436.

Abstract

Amarah, A, Petlin, D, Grice, J, Hadgraft, J, Roberts, M & Anissimov, Y 2018, 'Compartmental modeling of skin transport', European journal of pharmaceutics and biopharmaceutics, vol. 130, pp. 336-344.

Abstract

Arthur, A, Nguyen, TM, Paton, S, Klisuric, A, Zannettino, AC & Gronthos, S 2018, 'The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption', Scientific reports, vol. 8, article no. 12756, pp. 1-12.

Abstract

Bade, R, Stockham, P, Painter, B, Celma, A, Bijlsma, L, Hernandez, F, White, JM & Gerber, C 2018, 'Investigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data', Drug testing and analytics, in press, pp. 1-20.

Abstract

Bade, R, White, J & Gerber, C 2018, 'Qualitative and quantitative temporal analysis of licit and illicit drugs in wastewater in Australia using liquid chromatography coupled to mass spectrometry', Analytical and bioanalytical chemistry, vol. 410, no. 2, pp. 529-542.

Abstract

Barclay, TG, Hegab, HM, Michelmore, A, Weeks, M & Ginic-Markovic, M 2018, 'Multidentate polyzwitterion attachment to polydopamine modified ultrafiltration membranes for dairy processing: characterization, performance and durability', Journal of industrial and engineering chemistry, vol. 61, pp. 356-367.

Abstract

Beleigoli, AM, Andrade, AQ, Diniz, MdFH, Alvares, RS, Ferreira, MH, Silva, LA, Rodrigues, MC, Jacomassi, L, Cerqueira, AG & Ribeiro, AL 2018, 'Using the behaviour change wheel for designing an online platform for healthy weight loss - "POEmaS"', Studies in health technology and informatics, vol. 254, pp. 1-10.

Abstract

Beleigoli, AM, Queiroz De Andrade, A, Haueisen Diniz, MDF, Alvares, RS & Ribeiro, AL 2018, 'Online platform for healthy weight loss in adults with overweight and obesity - The "pOEmaS" project: A randomized controlled trial', BMC Public Health, vol. 18, no. 1, article no. 945, pp. 1-7.

Abstract

Bi, F, Song, D, Zhang, N, Liu, Z, Gu, X, Hu, C, Cai, X, Venter, H & Ma, S 2018, 'Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators', European journal of medicinal chemistry, vol. 159, pp. 90-103.

Abstract

Bogomolova, S, Zarnowiecki, D, Wilson, A, Fielder, A, Procter, N, Itsiopoulos, C, O'Dea, K, Strachan, J, Ballestrin, M, Champion, A & Parletta, N 2018, 'Dietary intervention for people with mental illness in South Australia', Health promotion international, vol. 33, no. 1, pp. 71-83.

Abstract

Botting, K, Loke, X, Zhang, S, Andersen, J, Nyengaard, J & Morrison, J 2018, 'Iugr decreases cardiomyocyte endowment and alters cardiac metabolism in a sex-and cause-of-iugr-specific manner', American journal of physiology, vol.315, no. 1, pp. R48-R67.

Abstract

Bu, X, Xiang, Y, Jin, W, Wang, J, Zhou, X & Wang, Y and 17 other authors 2018, 'Blood-derived amyloid-β protein induces Alzheimer's disease pathologies', Molecular psychiatry, online, pp. 1-9.

Abstract

Bui, TNT, Goldsworthy, S & Hotham, E 2018, 'Improving a pivotal hospital documentation tool utilised by clinical pharmacists', International journal of pharmacy practice, online, pp. 1-5.

Abstract

Cai, J, Huang, L, Huang, J, Kang, L, Lin, H, Huang, P, Zhu, P, Wang, J, Dong, J, Wang, L & Xian, CJ 2018, 'Associations between the cyclooxygenase-2 expression in circulating tumor cells and the clinicopathological features of patients with colorectal cancer', Journal of cellular biochemistry, online, pp. 1-7.

Abstract

Chiew, AL, Page, CB, Clancy, D, Mostafa, A, Roberts, MS & Isbister, GK 2018, '2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion', Clinical toxicology, v. 56, no. 5, pp. 377-380.

Abstract

Ciobanu, LG, Ferrari, AJ, Erskine, HE, Santomauro, DF, Charlson, FJ, Leung, J, Amare, AT, Olagunju, AT, Whiteford, HA & Baune, BT 2018, 'The prevalence and burden of mental and substance use disorders in Australia: findings from the Global Burden of Disease Study 2015', Australian and New Zealand journal of psychiatry, vol. 52, no. 5, pp. 483-490.

Abstract

Coates, A, Hill, A & Tan, S 2018, 'Nuts and Cardiovascular Disease Prevention', Current atherosclerosis reports, vol. 20, no. 10, article no. 48, pp. 1-19.

Abstract

Coombes, JA, Rowett, D, Whitty, JA & Cottrell, WN 2018, 'Use of a patient-centred educational exchange (PCEE) to improve patient's self-management of medicines after a stroke: a randomised controlled trial study protocol', BMJ open, vol. 8, no. 8, article no. e022225, pp. 1-9.

Abstract

Darby, JR & Morrison, JL 2018, 'And the beat goes on...', Journal of physiology, in press, pp. 1-5.

Abstract

Dening, TJ, Joyce, P & Prestidge, CA 2018, 'Improving correlations between drug solubilization and in vitro lipolysis by monitoring the phase partitioning of lipolytic species for lipid-based formulations', Journal of pharmaceutical sciences, pp. 1-33.

Abstract

Dening, TJ, Joyce, P, Webber, JL, Beattie, DA & Prestidge, CA 2018, 'Inorganic surface chemistry and nanostructure controls lipolytic product speciation and partitioning during the digestion of inorganic-lipid hybrid particles', Journal of Colloid and Interface Science.

Abstract

Dening, TJ, Thomas, N, Rao, S, Van Looveren, C, Cuyckens, F & Holm, R 2018, 'Montmorillonite and laponite clay materials for the solidification of lipid-based formulations for the basic drug blonanserin: in vitro and in vivo investigations', Molecular pharmaceutics.

Abstract

Dhillon, VS, Yeoh, E, Salisbury, C, Butters, J, Di Matteo, A, Olver, I & Fenech, M 2018, 'Cytokinesis block micronucleus cytome (CBMN Cyt) assay biomarkers and their association with radiation sensitivity phenotype in prostate cancer cases and DNA repair gene hOGG1 (C1245G) polymorphism', Environmental and molecular mutagenesis, online, pp. 1-9.

Abstract

Dong, J, Ma, X, Zhuge, Y & Mills, J 2018, 'Contact buckling behaviour of corrugated plates subjected to linearly varying in-plane loads', Steel and composite structures, vol.29, pp. 1-16.

Abstract

Eijkelkamp, BA, Begg, SL, Pederick, VG, Trapetti, C, Gregory, MK, Whittall, JJ, Paton, JC & McDevitt, CA 2018, 'Arachidonic acid stress impacts pneumococcal fatty acid homeostasis', Frontiers in microbiology, vol. 9, article no. 813, pp. 1-12.

Abstract

Ezard, N, Dunlop, A, Hall, M, Ali, R, McKetin, R, Bruno, R, Phung, N, Carr, A, White, J, Clifford, B, Liu, Z, Shanahan, M, Dolan, K, Baker, AL & Lintzeris, N 2018, 'LiMA: A study protocol for a randomised, double-blind, placebo controlled trial of lisdexamfetamine for the treatment of methamphetamine dependence', BMJ Open, vol. 8, no. 7, article no. e020723, pp. 1-9.

Abstract

Fanning, L, Vo, L, Ilomaki, J, Bell, JS, Elliott, RA & Darzins, P 2018, 'Validity of electronic hospital discharge prescription records as a source of medication data for pharmacoepidemiological research', Therapeutic advances in drug safety, vol. 9, no. 8, pp. 425-438.

Abstract

Faria, M, Björnmalm, M, Thurecht, KJ, Kent, SJ, Gooding, JJ, Parton, RG, Kavallaris, M, Johnston, AP, Corrie, SR, Boyd, BJ, Thordarson, P, Whittaker, AK, Stevens, MM, Prestidge, CA, Porter, CJ, Parak, WJ, Davis, TP, Crampin, EJ & Caruso, F 2018, 'Minimum information reporting in bio-nano experimental literature', Nature nanotechnology, vol. 13, no. 9, pp. 777-785.

Abstract

Fiorini, V, Bergamini, L, Monti, N, Zacchini, S, Plush, SE, Massi, M, Hochkoeppler, A, Stefan, A & Stagni, S 2018, 'Luminescent protein staining with Re(i) tetrazolato complexes', Dalton transactions, vol. 47, no. 28, pp. 9400-9410.

Abstract

Fullman, N, Yearwood, J, Abay, SM, Abbafati, C, Ciobanu, LG & Lozano, R and 864 other authors 2018, 'Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016', The lancet, vol. 391, no. 10136, pp. 2236-2271.

Abstract

Gadzhanova, S, Roughead, EE & Pont, LG 2018, 'Antidepressant switching patterns in the elderly', International psychogeriatrics, vol. 30, no. 9, pp. 1365-1374.

Abstract

Gillam, MH, Inacio, MC, Pratt, NL, Shakib, S & Roughead, EE 2018, 'Magnetic resonance imaging in people with cardiac implantable electronic devices: A population based cohort study', Heart lung and circulation, vol. 27, pp. 748-751.

Abstract

Gillam, MH, Kerr, M, Pratt, NL, Lim, R & Roughead, EE 2018, 'Mesh use in urogynaecological procedures between 2005 and 2016: an Australian cohort study', Australian and New Zealand journal of obstetrics and gynaecology, online, pp. 1-5.

Abstract

Gillam, MH, Pratt, NL, Inacio, MC, Shakib, S, Sanders, P, Lau, DH & Roughead, EE 2018, 'Rehospitalizations for complications and mortality following pacemaker implantation: a retrospective cohort study in an older population', Clinical cardiology, online, pp. 1-7.

Abstract

Grund, R, Stolarski, A & Stevens, M 2018, 'Rediscovery of Synemon selene (Lepidoptera: Castniidae) in the mid-north of South Australia', Transactions of the Royal Society of South Australia, online, pp. 1-6.

Abstract

Guo, Y, Wang, L-P, Li, C, Xiong, Y-X, Yan, Y-T, Zhao, L-Q, Li, S-D, Sun, J, Luo, H-Y & Xian, CJ 2018, 'Effects of ginsenoside Rb1 on expressions of phosphorylation Akt/phosphorylation mTOR/phosphorylation PTEN in artificial abnormal hippocampal microenvironment in rats', Neurochemical research, vol. 43, no. 10, pp. 1927-1937.

Abstract

Harrison, IP, Vinh, A, Johnson, IR, Luong, R, Drummond, GR, Sobey, CG, Tiganis, T, Williams, ED, O'Leary, JJ, Brooks, DA & Selemidis, S 2018, 'NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development', Oncotarget, vol. 9, no. 83, pp. 35378-35393.

Abstract

Hassanshahi, M, Su, YW, Fan, CM, Khabbazi, S, Hassanshahi, A & Xian, CJ 2018, 'Methotrexate chemotherapy-induced damages in bone marrow sinusoids: An in vivo and in vitro study', Journal of cellular biochemistry, online, pp. 1012.

Abstract

Hickey, EE, Wong, HS, Khazandi, M, Ogunniyi, AD, Petrovski, KR, Garg, S, Page, SW, O'Handley, R & Trott, DJ 2018, 'Repurposing Ionophores as novel antimicrobial agents for the treatment of bovine mastitis caused by Gram-positive pathogens', Journal of veterinary pharmacology and therapeutics, vol. 41, no. 5, pp. 746-754.

Abstract

Hickey, SM, Ashton, TD, Boer, G, Bader, CA, Thomas, M, Elliott, AG, Schmuck, C, Yu, HY, Li, J, Nation, RL, Cooper, MA, Plush, SE, Brooks, DA & Pfeffer, FM 2018, 'Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane', European journal of medicinal chemistry, vol. 160, pp. 9-22.

Abstract

Hill, E, Clifton, P, Goodwill, AM, Dennerstein, L, Campbell, S & Szoeke, C 2018, 'Dietary patterns and β-amyloid deposition in aging Australian women', Alzheimer's and dementia: translational research and clinical interventions, vol. 4, pp. 535-541.

Abstract

Hillen, JB, Vitry, A & Caughey, GE 2018, 'Medication-related quality of care in residential aged care: an Australian experience', International journal for quality in health care, online, pp. 1-9.

Abstract

Hoang, T, Liu, J, Pratt, N, Zheng, VW, Chang, KC, Roughead, E & Li, J 2018, 'Authenticity and credibility aware detection of adverse drug events from social media', International journal of medical informatics, vol. 120, pp. 101-115.

Abstract

Hoang, T, Liu, J, Pratt, N, Zheng, VW, Chang, KC, Roughead, E & Li, J 2018, 'Authenticity and credibility aware detection of adverse drug events from social media', International journal of medical informatics, vol. 120, pp. 157-171.

Abstract

Huang, L, Lin, H, Kang, L, Huang, P, Huang, J, Cai, J, Xian, Z, Zhu, P, Huang, M, Wang, L, Xian, CJ, Wang, J & Dong, J 2018, 'Aberrant expression of long noncoding RNA SNHG15 correlates with liver metastasis and poor survival in colorectal cancer', Journal of cellular physiology, online, pp. 1-8.

Abstract

Huang, M, Zeng, C, Yao, N, Zhang, J, Yan, B, Jiang, H, Tian, X, Ao, X, Zhao, H, Zhou, W, Chu, J, Wang, L, Xian, CJ, Zhang, Z & Wang, L 2018, 'Locally produced IGF-1 promotes hypertrophy of the ligamentum flavum via the mTORC1 signaling pathway', Cellular physiology and biochemistry, vol. 48, no. 1, pp. 293-303.

Abstract

Jiang, D, Mu, W, Pang, X, Liu, Y, Zhang, N, Song, Y & Garg, S 2018, 'Cascade cytosol delivery of dual-sensitive micelle-tailored vaccine for enhancing cancer immunotherapy', ACS applied materials and interfaces, vol. 10, no. 44,  pp. 37797-37811.

Abstract

Jiang, W, Zhang, H, Wu, J, Zhai, G, Li, Z, Luan, Y & Garg, S 2018, 'CuS@MOF-based well-designed Quercetin delivery system for chemo-photothermal therapy', ACS applied materials and interfaces, vol. 10, no. 40, pp. 34513-34523.

Abstract

Johnson, B, Zarnowiecki, D, Hendrie, G, Mauch, C & Golley, R 2018, 'How to reduce parental provision of unhealthy foods to 3- to 8-year-old children in the home environment? A systematic review utilizing the Behaviour Change Wheel framework', Obesity reviews, vol.19, no. 10, pp. 1359-1370.

Abstract

Joyce, P, Gustafsson, H & Prestidge, CA 2018, 'Engineering intelligent particle-lipid composites that control lipase-mediated digestion', Advances in colloid and interface science, online, pp. 1-23.

Abstract

Kalisch Ellett, LM, Lim, R, Pratt, NL, Kerr, M, Ramsay, EN, Leblanc, T V, Barratt, JD & Roughead, EE 2018, 'Reducing hypnotic use in insomnia management among Australian veterans: Results from repeated national interventions', BMC Health services research, vol.18, no. 1, article no. 626, pp. 1-10.

Abstract

Kalisch Ellett, L, Pratt, N & Roughead, E 2018, 'Analgesic use in Vietnam veterans' with musculoskeletal pain', Journal of military and veterans' health, vol. 26, no. 3, pp. 28-35.

Abstract

Kemp-Casey, A, Pratt, N, Ramsay, E & Roughead, EE 2018, 'Using post-market utilisation analysis to support medicines pricing policy: an Australian case study of aflibercept and ranibizumab use', Applied health economics and health policy, online, pp. 1-7.

Abstract

Khan, MS & Roberts, MS 2018, 'Challenges and innovations of drug delivery in older age', Advanced drug delivery reviews, in press, pp. 1-166.

Abstract

Kim, Y & Clifton, P 2018, 'Curcumin, cardiometabolic health and dementia', International journal of environmental research and public health, vol. 15, no. 10, pp. 1-34.  Kim, Y, Keogh, J & Clifton, P 2018, 'Probiotics, prebiotics, synbiotics and insulin sensitivity', Nutrition research reviews, vol. 31, no. 1, pp. 35-51.

Abstract

Kosari, S, Walker, E, Anderson, C, Peterson, G, Naunton, M, Castillo Martinez, E, Garg, S & Thomas, J 2018, 'Power outages and refrigerated medicines: The need for better guidelines, awareness and planning', Journal of clinical pharmacy and therapeutics, vol. 43, no. 5, pp. 737-739.

Abstract

Kruger, PC, Hirsh, J, Bhagirath, VC, Xu, K, Dale, B, de Vries, TA, Ginsberg, JS, Eikelboom, JW & Chan, NC 2018, 'In vitro reversal of the anti-aggregant effect of ticagrelor using untreated platelets', Thrombosis and haemostasis, vol. 118, no. 11, pp. 1895-1901.

Abstract

Kübler, E & Albrecht, H 2018, 'Large set data mining reveals overexpressed GPCRs in prostate and breast cancer: potential for active targeting with engineered anti-cancer nanomedicines', Oncotarget, vol. 9, no. 38, pp. 24882-24897. 

Abstract

Laba, TL, Reddel, HK, Zwar, NJ, Marks, GB, Roughead, E, Flynn, A, Goldman, M, Heaney, A, Lembke, K & Jan, S 2018, 'Does a patient-directed financial incentive affect patient choices about controller medicines for asthma? A discrete choice experiment and financial impact analysis', PharmacoEconomics, online, pp. 1-12.

Abstract

Lai, ECC, Shin, JY, Kubota, K, Man, KK, Park, BJ, Pratt, N, Roughead, E, Wong, IC, Kao Yang, YH & Setoguchi, S 2018, 'Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: A multi- database, international cohort study', Pharmacoepidemiology and drug safety, online, pp. 1-8.

Abstract

Lalic, S, Gisev, N, Ilomäki, J, Bell, JS & Korhonen, MJ 2018, 'Prevalence and incidence of prescription opioid analgesic use in Australia', British journal of clinical pharmacology, in press, pp. 1-31.

Abstract

Lalic, S, Jokanovic, N, Ilomäki, J, Gisev, N, Lloyd, B, Lubman, D I & Bell, JS 2018, 'Harms associated with extramedical use of prescription opioid analgesics in Australia: a scoping review', Research in social and administrative pharmacy, in press, pp. 1-11.

Abstract

Leavy, JM, Clifton, PM & Keogh, JB 2018, 'The role of choice in weight loss strategies: A systematic review and meta-analysis', Nutrients, vol. 10, no. 9, article no. 1136, pp. 1-13.

Abstract

Lee, AM, Bowen, JM, Su, Y-W, Plews, E, Chung, R, Keefe, DM & Xian, CJ 2018, 'Individual or combination treatments with lapatinib and paclitaxel cause potential bone loss and bone marrow adiposity in rats', Journal of cellular biochemistry, online, pp. 1-12.

Abstract

Li, WY, Li, XY, Tian, YH, Chen, XR, Zhou, J, Zhu, BY, Xi, HR, Gao, YH, Xian, CJ & Chen, K-M 2018, 'Pulsed electromagnetic fields prevented the decrease of bone formation in hindlimb-suspended rats by activating sAC/cAMP/PKA/CREB signaling pathway', Bioelectromagnetics, online, pp. 1-16.

Abstract

Liang, S, Dai, J, Niu, J, Wang, M, Wang, L & Dong, J 2018, 'Solidification of additives for zinc-contaminated silt', Advances in mechanical engineering, vol. 10, no. 7, pp. 1-13.

Abstract

Lim, E, Lim, R, Suhaimi, A, Chan, B & Wahab, A 2018, 'Treatment of chronic back pain using indirect vibroacoustic therapy: a pilot study', Journal of back and musculoskeletal rehabilitation, in press, pp. 1-7.

Abstract

Lim, R, Kerr, M & Roughead, EE 2018, 'Use of medicines and health services for chronic obstructive pulmonary disease among a cohort of Australians over 50 years', International journal of chronic obstructive pulmonary disease, vol. 2018, no. 13, pp. 3085-3093.

Abstract

Lin, Q, Lin, J, Yang, X, He, Y, Wang, L & Dong, J 2018, 'The effects of Mg²⁺ and Ba²⁺ dopants on the microstructure and magnetic properties of doubly-doped LaFeO₃ perovskite catalytic nanocrystals', Ceramics international, in press, pp. 1-8.

Abstract

Liu, S, Guo, W, Zhou, H, Tang, L, Feng, S, Zhong, JH & Zhou, XF 2018, 'proBDNF inhibits the proliferation and migration of OLN-93 oligodendrocytes', Molecular medicine reports, vol. 18, no. 4, pp. 3809-3817.

Abstract

Lock, MC, Tellam, RL, Botting, KJ, Wang, KC, Selvanayagam, JB, Brooks, DA, Seed, M & Morrison, JL 2018, 'The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults', Journal of physiology, online, pp. 1-16.

Abstract

Mohammed, YH, Holmes, A, Haridass, IN,  Sanchez, WY, Studier, H,  Grice, JE, Benson, HAE, & Roberts, MS 2018, 'Support for the Safe Use of Zinc Oxide Nanoparticle Sunscreens: Lack of Skin Penetration or Cellular Toxicity after Repeated Application in Volunteers'. Journal of investigative dermatology, in press, pp.1-2.

Abstract

Mokdad, AH, Charara, R, El Bcheraoui, C, Khalil, I, Ciobanu, LG & Murray, CJ and 183 other authors 2018, 'The burden of mental disorders in the Eastern Mediterranean region, 1990-2015: findings from the global burden of disease 2015 study', International journal of public health, vol. 63, no. S1, pp. 25-37.

Abstract

Mokdad, AH, Khalil, I, Collison, M, El Bcheraou, C, Ciobanu, LG & Murray, CJ and 179 other authors 2018, 'Maternal mortality and morbidity burden in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study', International journal of public health, vol. 63, suppl. 1, pp. S47-S61.

Abstract

Morley, KC, Baillie, A, Fraser, I, Furneaux-Bate, A, Dore, G, Roberts, M, Abdalla, A, Nghi, P & Haber, PS 2018, 'Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial', British journal of psychiatry, vol. 212, no. 6, pp. 362-369.

Abstract

Mowla, R, Wang, Y, Ma, S & Venter, H 2018, 'Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance', Biochimica et Biophysica Acta - Biomembranes, vol. 1860, no. 4, pp.878-886. 

Abstract

Murphy, KJ, Walker, KM, Dyer, KA & Bryan, J 2018, 'Estimation of daily intake of flavonoids and major food sources in middle-aged Australian men and women', Nutrition research, in press, pp. 1-68.

Abstract

Narayan, R, Nayak, UY, Raichur, AM & Garg, S 2018, 'Mesoporous silica nanoparticles: a comprehensive review on synthesis and recent advances', Pharmaceutics, vol. 10, no. 3, article no. 118, pp. 1-49.

Abstract

Neubauer, HA, Tea, MN, Zebol, JR, Gliddon, BL, Stefanidis, C, Moretti, PA, Pitman, MR, Costabile, M, Kular, J, Stringer, BW, Day, BW, Samuel, MS, Bonder, CS, Powell, JA & Pitson, SM 2018, 'Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma', Oncogene, online, pp. 1-15.

Abstract

Nguyen, H, Zarnowiecki, D, Segal, L, Gent, D, Silver, B & Boffa, J 2018, 'Feasibility of implementing infant home visiting in a Central Australian Aboriginal community', Prevention science, vol. 19, no. 7, pp. 966-976.

Abstract

Nguyen, TA, Knight, R, Mant, A, Razee, H, Brooks, G, Dang, TH & Roughead, EE 2018, 'Corruption practices in drug prescribing in Vietnam - an analysis based on qualitative interviews', BMC health services research, vol. 18, no. 1, article no. 587, pp. 1-20.

Abstract

Nguyen, TA, Nguyen, H, Pham, T, Nguyen, TH & Hinton, L 2018, 'A cluster randomized controlled trial to test the feasibility and preliminary effectiveness of a family dementia caregiver intervention in Vietnam: the REACH VN study protocol', Medicine, vol. 97, no. 42, article no. e12553, pp. 1-5.

Abstract

Nielsen, S, Macdonald, T & Johnson, JL 2018, 'Identifying and treating codeine dependence: A systematic review', Medical journal of Australia, vol. 208, no. 10, pp. 451-461.

Abstract

Ofori-Asenso, R, Ilomaki, J, Tacey, M, Curtis, AJ, Zomer, E, Bell, JS, Zoungas, S & Liew, D 2018, 'Prevalence and incidence of statin use and 3-year adherence and discontinuation rates among older adults with dementia', American journal of Alzheimer's disease and other dementias, online, pp. 1-8.

Abstract

Page, TJ, Stevens, M I, Adams, M, Foster, R, Velasco-Castrillon, A & Humphreys, WF 2018, 'Multiple molecular markers reinforce the systematic framework of unique Australian cave fishes (Milyeringa: Gobioidei)', Australian journal of zoology, online, pp. 1-13.

Abstract

Pansara, C, Chan, WY, Parikh, AY, Trott, DJ, Mehta, T, Mishra, R & Garg, S 2018, 'Formulation optimization of chitosan stabilised silver nanoparticles using in-vitro antimicrobial assay', Journal of pharmaceuticalsSciences, in press, pp. 1-33.

Abstract

Paparella, AS, Feng, J, Blanco-Rodriguez, B, Feng, Z, Phetsang, W, Blaskovich, MA, Cooper, MA, Booker, GW, Polyak, SW & Abell, AD 2018, 'A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase', Tetrahedron, vol. 74, no. 12, pp. 1175-1183.

Abstract

Paparella, AS, Lee, KJ, Hayes, AJ, Feng, J, Feng, Z, Cini, D, Deshmukh, S, Booker, GW, Wilce, MC, Polyak, SW & Abell, AD 2018, 'Halogenation of biotin protein ligase inhibitors improves whole cell activity against Staphylococcus aureus', ACS infectious diseases, vol. 4, no. 2, pp. 175-184.

Abstract

Parikh, A, Kathawala, K, Li, J, Chen, C, Shan, Z, Cao, X, Zhou, X-F & Garg, S 2018, 'Curcumin-loaded self-nanomicellizing solid dispersion system: part II: in vivo safety and efficacy assessment against behavior deficit in Alzheimer disease', Drug delivery and translational research, vol. 8, no. 5, pp. 1406-1420.

Abstract

Parikh, A, Kathawala, K, Song, Y, Zhou, XF & Garg, S 2018, 'Curcumin-loaded self-nanomicellizing solid dispersion system: part I: development, optimization, characterization, and oral bioavailability', Drug delivery and translational research, vol. 8, no. 5, pp. 1389-1405.

Abstract

Pavathuparambil Abdul Manaph, N, Al-Hawaas, M, Bobrovskaya, L, Coates, PT & Zhou, XF 2018, 'Urine-derived cells for human cell therapy', Stem cell research and therapy, vol. 9, no. 1, article no. 189, pp. 1-12.

Abstract

Pavathuparambil Abdul Manaph, N, Al-Hawwas, M, Liu, L, Liu, D, Hayball, J & Zhou, XF 2018, 'Facial vein injection of human cells in severe combined immunodeficiency (SCID) neonatal mice', MethodsX, vol. 5, pp. 1281-1286. 

Abstract

Pawliszak, P, Zawala, J, Ulaganathan, V, Ferri, JK, Beattie, DA & Krasowska, M 2018, 'Interfacial characterisation for flotation: 2. Air-water interface', Current opinion in colloid & interface science, vol. 37, pp. 115-127.

Abstract

Pitson, SM & Powell, JA 2018, 'Modification of the tumour microenvironment via exosomal shedding of sphingosine 1-phosphate receptor 2 by breast cancer cells', OncoTarget, vol. 9, no. 57, pp. 30938-30939.

Abstract

Pollard, G, Roetman, P, Ward, J, Chiera, B & Mantzioris, E 2018, 'Beyond productivity: considering the health, social value and happiness of home and community food gardens', Urban science, vol. 2, no. 4, pp. 1-16. 

Abstract

Porter, JA, MacKenzie, KE, Darlow, BA, Butler, R & Day, AS 2018, 'Gastric emptying in children with type 1 diabetes mellitus: A pilot study', Journal of paediatrics and child health, online, pp. 1-5.

Abstract

Prosser, AE, Dawson, JL, Koo, K, O'Kane, KM, Ward, MB, Woodman, RJ, Mangoni, AA & Phillips, CJ 2018, 'Real-world incidence of patient-reported dyspnoea with ticagrelor', Therapeutic advances in drug safety, vol. 9, no. 10, pp. 577-584.

Abstract

Prow, NA, Jimenez Martinez, R, Hayball, JD, Howley, PM & Suhrbier, A 2018, 'Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines', Expert review of vaccines, vol. 17, no. 10, pp. 925-934.

Abstract

Qin, T, Huang, D, Liu, Z, Zhang, X, Jia, Y, Xian, CJ & Li, K 2018, 'Tumor necrosis factor superfamily 15 promotes lymphatic metastasis via upregulation of vascular endothelial growth factor-C in a mouse model of lung cancer', Cancer science, vol. 109, no. 8, pp. 2469-2478.

Abstract

Rahaman, MH, Yu, Y, Zhong, L, Adams, J, Lam, F, Li, P, Noll, B, Milne, R, Peng, J & Wang, S 2018, 'CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia', Investigational new drugs, online, pp. 1-11.

Abstract

Raman, SR, Man, KK, Bahmanyar, S, Berard, A, Pratt, NL, Roughead, EE & Wong, IC and 26 other authors 2018, 'Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases', Lancet psychiatry, vol. 5, no. 10, pp. 824-835.

Abstract

Rasmussen, L, Pratt, N, Hansen, MR, Hallas, J & Pottegård, A 2018, 'Using the 'proportion of patients covered' and the Kaplan-Meier survival analysis to describe treatment persistence', Pharmacoepidemiology and drug safety.

Abstract

Rasmussen, L, Pratt, N, Roughead, E & Moffat, A 2018, 'Prevalence of psychotropic medicine use in Australian children with autism spectrum disorder: A drug utilization study based on children enrolled in the Longitudinal study of Australian children', Journal of autism and developmental disorders, online, pp. 1-9.

Abstract

Roughead, E, Kim, DS, Ong, B & Kemp-Casey, A 2018, 'Pricing policies for generic medicines in Australia, New Zealand, the Republic of Korea and Singapore: patent expiry and influence on atorvastatin price', WHO South-East Asia journal of public health, vol. 7, no. 2, pp. 99-106.

Abstract

Satiaputra, J, Eijkelkamp, BA, McDevitt, CA, Shearwin, KE, Booker, GW & Polyak, SW 2018, 'Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin', Applied microbiology and biotechnology, vol. 102, no. 8, pp. 3793-3803.

Abstract

Senthilkumaran, M, Bobrovskaya, L, Verberne, A & Llewellyn-Smith, I 2018, 'Insulin‐responsive autonomic neurons in rat medulla oblongata', Journal of comparative neurology, in press, pp. 1-59.

Abstract

Sharkey, DJ, Glynn, DJ, Schjenken, JE, Tremellen, KP & Robertson, SA 2018, 'Interferon-gamma inhibits seminal plasma induction of colony-stimulating factor 2 in mouse and human reproductive tract epithelial cells', Biology of reproduction, vol. 99, no. 3, pp. 514-526.

Abstract

Shirmohammadi, M, Charrault, E & Blencowe, A 2018, 'Micromechanical properties of almond kernels with various moisture content levels', International journal of food properties, vol. 21, no. 1, pp. 1820-1832. 

Abstract

Solomon, LB, Kitchen, D, Anderson, PH, Yang, D, Starczak, Y, Kogawa, M, Perilli, E, Smitham, PJ, Rickman, MS, Thewlis, D & Atkins, GJ 2018, 'Time dependent loss of trabecular bone in human tibial plateau fractures', Journal of orthopaedic research, online, pp. 1-11.

Abstract

Sriskandarajah, S, Hobbs, J, Roughead, E, Ryan, M & Reynolds, K 2018, 'Safety and effectiveness of 'hospital in the home' and 'outpatient parenteral antimicrobial therapy' in different age groups: A systematic review of observational studies', International journal of clinical practice, vol. 72, no. 8, article no. e13216, pp. 1-15.

Abstract

Su, YW, Chim, SM, Zhou, L, Hassanshahi, M, Chung, R, Fan, C, Song, Y, Foster, BK, Prestidge, CA, Peymanfar, Y, Tang, Q, Butler, LM, Gronthos, S, Chen, D, Xie, Y, Chen, L, Zhou, XF, Xu, J & Xian, CJ 2018, 'Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats', Bone, vol. 116, pp. 232-247.

Abstract

Theou, O, Sluggett, JK, Bell, JS, Lalic, S, Cooper, T, Robson, L, Morley, JE, Rockwood, K & Visvanathan, R 2018, 'Frailty, hospitalization, and mortality in residential aged care', Journals of gerontology series A-biological sciences and medical sciences, vol. 73, no. 8, pp. 1090-1096.

Abstract

Wanandy, T, Wilson, R, Gell, D, Rose, HE, Gueven, N, Davies, NW, Brown, SG & Wiese, MD 2018, 'Towards complete identification of allergens in Jack Jumper (Myrmecia pilosula) ant venom and their clinical relevance: An immunoproteomic approach', Clinical and experimental allergy, vol. 48, no. 9, pp. 1222-1234.

Abstract

Wang, Y-Y, Pu, XY, Shi, W-G, Fang, Q-Q, Chen, X-R, Xi, H-R, Gao, Y-H, Zhou, J, Xian, CJ & Chen, K-M 2018, 'Pulsed electromagnetic fields promote bone formation by activating the sAC-cAMP-PKA-CREB signaling pathway', Journal of cellular physiology, online, pp. 1-15.

Abstract

Warland, J, Dorrian, J, Kember, AJ, Phillips, C, Borazjani, A, Morrison, JL & O'Brien, LM 2018, 'Modifying maternal sleep position in late pregnancy through positional therapy: a feasibility study', Journal of clinical sleep medicine, vol. 14, no. 8, pp. 1387-1397.

Abstract

Westaway, K, Sluggett, J, Alderman, C, Moffat, A, Procter, NG & Roughead, E 2018, 'The extent of antipsychotic use in Australian residential aged care facilities and interventions shown to be effective in reducing antipsychotic use: A literature review', Dementia, online, pp. 1-14.

Abstract

Widagdo, IS, Pratt, NL & Roughead, EE 2018, 'The association between frailty and medicines use over time: an analysis using the Australian Longitudinal Study on Ageing population', Journal of pharmacy practice and research, online, pp. 1-11.

Abstract

Wines, BD, Tan, CW, Duncan, E, McRae, S, Baker, R I, Andrews, RK, Esparon, S, Gardiner, EE & Hogarth, PM 2018, 'Dimeric FcγR ectodomains detect pathogenic platelet factor 4‐heparin antibodies in heparin induced thromobocytopenia', Journal of thrombosis and haemostasis, in press, pp. 1-16.

Abstract

Wong, SS & Ngo, SN 2018, 'Use of in vitro dissolution testing to assess multiple generic metformin tablets', British journal of pharmaceutical research, vol. 21, no. 4, article no. 39508, pp. 1-9.

Abstract

Yamada, M, Tayeb, H, Wang, H, Dang, N, Mohammed, YH, Osseiran, S, Belt, PJ, Roberts, M, Evans, CL, Sainsbury, F & Prow, TW 2018, 'Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers', Journal of controlled release, vol. 288, pp. 264-276.

Abstract

Zhan, C, Roughead, E, Liu, L, Pratt, N & Li, J 2018, 'A data-driven method to detect adverse drug events from prescription data', Journal of biomedical informatics, vol. 85, pp. 10-20.

Abstract

Zhang, Y, Liu, Y-X, Xiao, Q-X, Liu, Q, Deng, R, Bien, J, Deng, IB, Al-Hawwas, M & Yu, F-X 2018, 'Microarray expression profiles of lncRNAs and mRNAs in postoperative cognitive dysfunction', Frontiers In Neuroscience.

Abstract