Biosafety

               To protect each other, our health, our environment, our economy

                and our research, we must continue to engage in biosafety practices

at the highest level.

Spills and Incidents

Phone numbers and contacts

Spills procedures

Incident reporting

Reporting an unintentional release of a GMO

Disinfectants - The perfect match for your bug

Security Sensitive Biological Agents- What to do if you suspect the use of an SSBA

Projects Involving Biological Material

Biological hazardous material is defined as organic substances that pose a threat to the health of humans and other living organisms. Biological hazards include pathogenic microorganisms, viruses, toxins (from biological sources), spores, fungi and bio-active substances. Biological hazards can also be considered to include biological vectors or transmitters of disease. Here is a list of some common sources of biologically hazardous materials.

Work involving either unmodified or genetically modified biological material must be risk assessed by the Institutional Biosafety Committee (IBC) prior to commencing teaching or research.

 

IBC Application Requirements

*Definition of SDN1

For clarification contact biosafety@unisa.edu.au. 

Unmodified Hazardous Biological Material

Instititional Biosafety Committee assessment is required before hazardous biological material is used. 

Application Forms

Biological Hazard Application Form

To start a new application select in the left hand panel - Workspaces > BCR Process > BCR Process > +New

 

Handy Hint

To determine the risk rating of a wild-type microorganism or cell line, refer to AS/NZS 2243.3 or the manufacturer's Material Safety Data Sheet.

 

Minor Modifications

An amendment application can be submitted to add personnel or facilities to an IBC approved biological process .

If the application was submitted via the online BCR module, changes can be requested via the ‘Change Requests’ tab in the approved BCR application. 

If the application was submitted via a Word form, changes can be requested via submission of the 

  Amendment Application Form  

After obtaining signature(s) of Lab Manager/Coordinator(s), send the amendment application form

to IBC biosafety@unisa.edu.au.

Genetically Modified Organisms

Use of genetically modified organisms requires IBC approval before project commencement. Details and application forms can be found on the

Gene Technology webpage.

 

Biosafety Officer Approval For New Accounts With ATCC

For Biosafety Officer approval to establish an account with ATCC, email biosafety@unisa.edu.au with the:

  • ATCC application form and
  • Material Safety Data Sheet for the ATCC cell line you wish to purchase.

Before signing, the Biosafety Officer will check that appropriate facilities and risk management strategies are in place.

 

"We engage in biosafety and biosecurity not because the Regulations tell us to, but because we belong to a community that cares about research, each other and the environment."

Biosafety Training

When working with biologicals, it is important that we don't over estimate our biosafety knowledge and underestimate the risks. Biosafety training is important in avoiding those pitfalls and keeping you and your colleagues safe. 

Completion of the online Biosafety 1 training module and laboratory induction are compulsory for all new staff and research students wishing to work with biological material. 

It is the responsibility of Research Leaders and Facility Managers to ensure they and the staff and students directly under their supervision, are adequately trained to manage hazardous biological material and GMOs.

Training should include:

  • laboratory induction,
  • online Biolocial Safety training module,
  • if working in an OGTR certified facility, reading and understanding the behavioural requirements of OGTR conditions for PC2 facilities,
  • if using GMOs, reading and understanding the Gene Technology Guidelines for transport, storage and disposal,
  • face-to-face competence confirmed training for high risk procedures,
  • spills and sharps training,
  • attendance of the Biosafety Information Seminars at least once every five years,
  • reading and understanding of the Academic Unit/Institute/Centre laboratory biosafety manual

UniSA Research Office and the IBC offer training program support. For support and further information contact: biosafety@unisa.edu.au.

Current Biocontainment Facilities and Signatories

Work involving genetically modified organisms must be conducted in OGTR certified facilities of the same or higher physical containment rating. Exempt GMOs must only be used in OGTR certified facilities of PC1 or higher.

Work involving GMOs must only be conducted within facilities suitable to contain the organism. For example, GM insects can only be used in an OGTR certified PC1 or higher insectary, not in a standard laboratory.

Work involving non-GM organisms of Risk Group 1 or higher grouping, must be conducted in either an IBC classified or OGTR certified biocontainment facility, of equal or higher PC rating.

List of Biocontainment Facilities and Signatories

Import, Export and Transfer of Biologicals

Whether biological goods are transferred internationally, interstate or just next door there are a number of items to organise. For details see the Biosecurity webpages.

Regulations and Standards

Biosafety Manual

University’s biosafety management system and regulatory requirements for working with infectious microorganisms and genetically modified organisms.

Australian and New Zealand Standards for Safety In Laboratories: Microbiological Safety and Containment

Electronic copies can be accessed through the UniSA Library.

Recommended way to find the Standards:

  • Go to the UniSA Library webpage and find the A-Z Databases list, Library Database T
  • Select Techstreet: Standards Australia.
  • Under "View Online" select “Sign in”  
  • Sign in with your UniSA staff or student Username and Password
  • Select Techstreet Enterprise
  • Login to the standards with your UniSA staff or student login
  • Search for AS/NZS 2243.3

Gene Technology Regulator Guidelines for Storage, Transport and Disposal of Genetically Modified Organisms

Security Sensitive Biological Agents

Important Note: There are no facilities within South Australia currently available to undertake research using SSBAs.

For Biological Hazards applications involving the use of Security Sensitive Biological Agents (SSBA), please check the SSBA website (Department of Health), and SSBA newsletters (published monthly).

National Health Security Regulations 2018

National Health Security Act 2007

Defence Export Controls

Controls are placed on biological material which can be used for military purposes. Export restrictions include not only the export of physical (tangible) goods and technology, but also the supplypublication or brokering of controlled technology by electronic or other non-physical (intangible) means. For further information and a self-assessment tool see our Defence Export Controls webpage.

 

 

Vaccination for Staff and Research Degree Students

Staff and Research Degree Students who handle human or animal blood, tissue, excrement or body fluids, soil, unaged compost, pathogenic bacteria, prions, parasites or viruses are often at risk of occupational exposure to vaccine-preventable diseases. Personnel considered at high risk are those in direct physical contact, contact with contaminated surfaces/equipment or exposed to infection by the respiratory route.

Immunisation of Research Staff and Students  

To determine if research personnel are at risk of infection of vaccine-preventable diseases, Research Group Leaders will conduct a risk assessment as part of their IBC application to use biologicals. The UniSAfe BCR application form will ask Research Group Leaders specific questions regarding the type of biological material handled, the potential route of infection, and the project procedures.

 

The type of recommended vaccinations can be found in the Australian Immunisation Handbook. Vaccinations recommended for laboratory workers and people working with blood and body fluids are listed in the 'Vaccination for people at occupational risk' webpage of the AIH.

 

The IBC will review the application and assess the risks on a case-by-case basis. ​If the IBC considers the project poses a risk of infection, the IBC will ratify the immunisation recommendations.

 

Immunisation of Technical and Professional Staff

Vaccination is also available for technical and professional staff at risk of occupational exposure to vaccine preventable diseases.

Line Managers should:

  • Complete a Technical and Professional Staff Risk Assessment Form to determine the need for vaccination of technical and professional staff.
  • After completing the Technical and Professional Staff Risk Assessment Form, Line Managers should submit the staff risk assessment form to the IBC, biosafety@unisa.edu.au. The IBC will ratify the risk assessment and immunisation recommendations.

For Everyone – Required Documents:

Staff and Research Degree students requiring vaccination should be given a vaccination form to take to either the UniSA Health Medical Clinic or General Practitioner. For record keeping personnel should return the completed form to the Operations/General Manager of their Academic Unit, Institute or Centre.

Funding

Cost of vaccination can be charged directly to either Academic Unit, Institute, Centre, Portfolio or research project funding.  If personnel use the UniSA Health Medical Clinic, a claim can be submitted directly to these funds, avoiding the need for upfront payment. To claim on this system a fs32 form must be completed and submitted to the UniSA Health Medical Clinic. Alternatively, personnel may use their own General Practioner or Travel Doctor and then seek reimbursement through their Research Group Leader or Line Manager.

A schematic representation of processes (600kb) is available. Further information is available through the Biosafety Officer, biosafety@unisa.edu.au.

Conflicts of Interest

Members of the Institutional Biosafety Committee register their personal interests which may be perceived by others to conflict with their unbiased assessment of applications. Conflicted members do not read or vote on applications or matters with which they are conflicted.

Applicants are welcome to discuss any concerns about conflicts of interest and request that a specific IBC member not review a matter, by contacting the Executive Officer biosafety@unisa.edu.au.

UniSA Support

  • UniSA Biosafety Officer and IBC: biosafety@unisa.edu.au (Ph. 830 23723)
  • Cell Sorting Facility Manager: Bradley.Chereda@unisa.edu.au
  • Principal Investigator of your project
  • Your Senior Facility Manager
  • Your Operations/General Manager
  • Safety and Wellbeing: SafetyWellbeing@unisa.edu.au 

Anonymous Reporting

Have you witnessed a supervisor encouraging unsafe biosafety practises?

Have you seen a colleague engaging in unsafe practices?

Are you concerned that the personal protective equipment is inadequate to provide safety?

Are you concerned about a potential misuse or dangerous modification of a genetically modified organism?

For any of these situations or others of concern, we invite you to contact the Biosafety Officer, biosafety@unisa.edu.au, or the Manager of Research Integrity, researchintegrity@unisa.edu.au.

Your name and personal details will not be revealed to anyone, including the Institutional Biosafety Committee.